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POINT Biopharma, Isotopia Ink Lutetium-177 Clinical Supply Agreement

POINT Biopharma Global Inc (NASDAQ: PNT) and Isotopia Molecular Imaging Limited have signed a clinical supply agreement for the medical radioisotope no-carrier-added Lutetium-177 (Lu-177), a therapeutic isotope used in POINT’s pipeline.

  • The 6.6-day half-life of Lu-177 is sufficiently short for use with various radiopharmaceuticals and long enough to minimize decay loss during the preparation and shipping of the radiopharmaceutical. 
  • Lu-177 damages tumors when bound to disease-specific targeting therapeutics, such as POINT’s PSMA targeting drug candidate PNT2002 for metastatic castration-resistant prostate cancer (mCRPC). 
  • Isotopia has developed a GMP method to produce a highly pure form of n.c.a. Lu-177. Isotopia’s Lu-177 contains no metastable Lu-177m, eliminating cost-intensive clinical waste management. 
  • Isotopia’s Lu-177 will be used at POINT’s Indianapolis facility to manufacture its therapeutic radioligand therapies.
  • Price Action: PNT shares are up 0.50% at $8.11 during the market session on the last check Wednesday.

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